Sicklepod seed 決明子
Pharmaceutical nameCassiae Semen
The three axes are assessed independently and are never combined into a single score.
KTKP records the origin species as Cassia obtusifolia L.. It has not yet been cross-checked against the Korean Pharmacopoeia, so the identification confidence is not raised to an official code mapping. The same drug appears under 3 records as name variants. The name most used for this taxon in current literature is Cassia obtusifolia. Literature searches for this herb also cover Senna obtusifolia — the same taxon appears under several names. The nomenclatural discussion for this herb was flagged for correction during verification; only the verified facts are shown here, with the details in docs/HERB_NAME_RESEARCH.md.
Tradition · what the text describes
탕액편
The sub-section within this volume has not been verified against the original text yet.
The KTKP traditional materia medica record (M0000146) gives the origin species as Cassia obtusifolia L., the part used as 씨, and the properties as 감고(甘苦), 미한(微寒). It lists 간(肝), 대장(大腸) as the channels entered. The same record cites the Donguibogam (1613) as the source for its indications.
Properties & channel entry: 감고(甘苦), 미한(微寒) · 간(肝), 대장(大腸)
Source species: Cassia obtusifolia L. (씨)
Modern · documented evidence
Obesityevidence for this indication
- The indication was derived automatically from the Condition field of 0 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 1 · preclinical 1
0 systematic review(s) and 1 RCT(s) were found. Size and consistency are not yet assessed.
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Cassia obtusifolia") OR (TITLE_ABS:"Senna obtusifolia")) AND TITLE_ABS:"Obesity"- Bioactive compounds with anti-obesity potential from Cassia obtusifolia L. explored by lipase-immobilized magnetic metal-organic frameworks and UPLC-Q-TOF-MS/MS. (2025 · Journal Article)
- Pharmacological properties and underlying mechanisms of aurantio‑obtusin (Review). (2023 · Review; Journal Article)
- Oral administration of processed Cassia obtusifolia L. seed powder May reduce body weight and cholesterol in overweight patients with schizophrenia: A 36-week randomized, double-blind, controlled trial of high and low doses. (2022 · Randomized Controlled Trial; Journal Article)
- How does traditional knowledge of Cassiae semen shed light on weight management? - A classical and modern literature review. (2021 · Review; Journal Article)
Clinical trials
- NCT05632068 — UNKNOWN · PHASE3
- NCT05548842 — COMPLETED · NA
- NCT04252131 — COMPLETED · PHASE1
Safety
auto-proposed · unreviewed
- 14 adverse-event or toxicity record(s) were found. This only flags that literature exists — read the abstracts to decide between "caution" and "harm confirmed".
- The KTKP record states the following traditional contraindication: 대마자(大麻子)와 상오(相惡)함.
Adverse-event and toxicity literature
This is not a finding of harm — it lists literature that is retrievable. Read the papers to decide.
- Toxic myopathy in dairy goats caused by spontaneous ingestion of Senna obtusifolia. (2026 · Journal Article)
- Study on Translational toxicology of Senna obtusifolia aqueous extract. (2024 · Journal Article)
- Toralactone alleviates cisplatin-induced acute kidney injury by modulating the gut microbiota-renal axis. (2024 · Journal Article)
- Assessment of Lead (Pb) Remediation Potential of Senna obtusifolia in Dareta Village, Zamfara, Nigeria. (2020 · research-article; Journal Article)
- Predicting the potential toxicity of 26 components in Cassiae semen using in silico and in vitro approaches. (2021 · research-article; Journal Article)