Cassia bark 肉桂
Pharmaceutical nameCinnamomi Cortex Spissus
The three axes are assessed independently and are never combined into a single score.
KTKP records the origin species as Cinnamomum cassia Blume. It has not yet been cross-checked against the Korean Pharmacopoeia, so the identification confidence is not raised to an official code mapping. The same drug appears under 5 records as name variants. The same source species also yields 2 other separately registered drug(s) (Cinnamomi Ramulus, Cinnamomi Cortex Interior), which must not be conflated. The name most used for this taxon in current literature is Cinnamomum cassia. Literature searches for this herb also cover Cinnamomum aromaticum — the same taxon appears under several names. The nomenclatural discussion for this herb was flagged for correction during verification; only the verified facts are shown here, with the details in docs/HERB_NAME_RESEARCH.md.
Tradition · what the text describes
탕액편
The sub-section within this volume has not been verified against the original text yet.
The KTKP traditional materia medica record (M0000199) gives the origin species as Cinnamomum cassia Blume, the part used as 껍질, and the properties as 신감(辛甘), 열(熱). It lists 간(肝), 비(脾), 신(腎), 심(心) as the channels entered. The same record cites the Donguibogam (1613) as the source for its indications.
Properties & channel entry: 신감(辛甘), 열(熱) · 간(肝), 비(脾), 신(腎), 심(心)
Source species: Cinnamomum cassia Blume (껍질)
Modern · documented evidence
Diabetes Mellitus, Type 2evidence for this indication
- 2 registered trial(s) exist but no published systematic review or RCT was found. Check whether the research is ongoing or simply unpublished.
- The indication was derived automatically from the Condition field of 2 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 0 · preclinical 0
No human studies were found within the sources searched. This means "not yet studied", not "does not work".
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Cinnamomum cassia") OR (TITLE_ABS:"Cinnamomum aromaticum")) AND TITLE_ABS:"Diabetes Mellitus, Type 2"Clinical trials
- NCT06140485 — UNKNOWN · PHASE3
- NCT03610412 — COMPLETED · PHASE3
Polycystic Ovary Syndromeevidence for this indication
- 2 registered trial(s) exist but no published systematic review or RCT was found. Check whether the research is ongoing or simply unpublished.
- The indication was derived automatically from the Condition field of 2 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 0 · preclinical 0
No human studies were found within the sources searched. This means "not yet studied", not "does not work".
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Cinnamomum cassia") OR (TITLE_ABS:"Cinnamomum aromaticum")) AND TITLE_ABS:"Polycystic Ovary Syndrome"- Herbal medicine for the management of polycystic ovary syndrome (PCOS) and associated oligo/amenorrhoea and hyperandrogenism; a review of the laboratory evidence for effects with corroborative clinical findings. (2014 · research-article; Review; Journal Article)
Clinical trials
- NCT03778099 — COMPLETED · PHASE3
- NCT04120597 — COMPLETED · PHASE1, PHASE2
Safety
auto-proposed · unreviewed
- This signal was read off the NCCIH text by keyword rules. A curator must read the source and confirm it.
- The NCCIH page covers the genus Cinnamomum generally, not this species alone.
- The KTKP record states the following traditional contraindication: 양허음성자(陽虛陰盛者)와 임부는 쓰지 말 것.
- NCCIH states: When used in larger amounts or for long periods of time, cinnamon is sometimes associated with side effects, most commonly gastrointestinal problems or allergic reactions.
- NCCIH states: · According to research partially funded by the National Center for Complementary and Integrative Health, there are theoretical reasons to suspect that some components of cinnamon may interact with an anticancer medicine or nicotine.
- NCCIH states: · Some studies of the use of Ceylon and cassia cinnamon during pregnancy suggest it is safe in amounts commonly found in foods, but Ceylon cinnamon in larger amounts during pregnancy is considered unsafe.
- NCCIH states: Little is known about whether it’s safe to use Ceylon or cassia cinnamon in larger amounts while breastfeeding.
Adverse-event and toxicity literature
This is not a finding of harm — it lists literature that is retrievable. Read the papers to decide.
- Retraction Note: Assessment of Titanium Dioxide Nanoparticles (TiO2-NPs) Induced Hepatotoxicity andAmeliorative Effects of Cinnamomum cassia in Sprague-Dawley Rats. (2025 · Retraction Notice)
- Guizhi Gancao Decoction protects against doxorubicin-induced cardiotoxicity by intervening in microtubule acetylation. (2026 · Journal Article)
- A Phase 2, Multi-Center, Randomized, Double-Blind, Parallel-Group Trial to Evaluate the Efficacy and Safety of CKD-495 in Patients With Acute and Chronic Gastritis. (2025 · Clinical Trial, Phase II; Research Support, Non-U.S. Gov't; research-article; Multicenter Study; Randomized Controlled Trial; Journal Article)
- Chinese herbal foot baths as a new strategy for diabetic foot with Wagner grade of 0 or 1: a meta-analysis and data mining. (2025 · Systematic Review; systematic-review; Journal Article)
- Efficacy and safety of CKD-495 in acute and chronic gastritis: A Phase III superiority clinical trial. (2023 · Clinical Trial, Phase III; Equivalence Trial; research-article; Multicenter Study; Randomized Controlled Trial; Journal Article)
Interaction literature
This lists literature that is retrievable — it is not a judgement that an interaction exists. Read the papers to decide.
- A nutraceutical combination of Cinnamomum cassia &Nigella sativa for Type 1 diabetes mellitus. (2018 · research-article; Journal Article)
- Potential Targets for Treatment of Coronavirus Disease 2019 (COVID-19): A Review of Qing-Fei-Pai-Du-Tang and Its Major Herbs. (2020 · Historical Article; Review; Journal Article)
Sources
- KTKP materia medica (15002148) (fetched 2026-08-27)
- Europe PMC REST (fetched 2026-08-28)
- ClinicalTrials.gov API v2 (fetched 2026-08-28)
- Europe PMC REST (fetched 2026-08-28)
- ClinicalTrials.gov API v2 (fetched 2026-08-28)
- KTKP materia medica (15002148) (fetched 2026-08-27)
- NCCIH Herbs at a Glance (fetched 2026-08-27)
Bridges from here
- In formulas
- 계령탕 · 계출탕 · 생료오적산 · 내탁천금산 · 분심기음
- Related patterns
- Wind-cold pattern · Qi phase pattern · Blood phase pattern