Gardenia fruit 梔子
Pharmaceutical nameGardeniae Fructus
The three axes are assessed independently and are never combined into a single score.
KTKP records the origin species as Gardenia jasminoides J. Ellis (= Gardenia jasminoides for. grandiflora). It has not yet been cross-checked against the Korean Pharmacopoeia, so the identification confidence is not raised to an official code mapping. The same drug appears under 5 records as name variants. The same source species also yields 1 other separately registered drug(s) (Gardeniae Semen), which must not be conflated. The name most used for this taxon in current literature is Gardenia jasminoides. Literature searches for this herb also cover Gardenia augusta, Gardenia florida — the same taxon appears under several names.
Tradition · what the text describes
탕액편
The sub-section within this volume has not been verified against the original text yet.
The KTKP traditional materia medica record (M0001780) gives the origin species as Gardenia jasminoides J. Ellis (= Gardenia jasminoides for. grandiflora), the part used as 열매, and the properties as 고(苦), 한(寒). It lists 삼초(三焦), 심(心), 폐(肺) as the channels entered. The same record cites the Donguibogam (1613) as the source for its indications.
Properties & channel entry: 고(苦), 한(寒) · 삼초(三焦), 심(心), 폐(肺)
Source species: Gardenia jasminoides J. Ellis (= Gardenia jasminoides for. grandiflora) (열매)
Modern · documented evidence
Overweight and Obesityevidence for this indication
- 2 registered trial(s) exist but no published systematic review or RCT was found. Check whether the research is ongoing or simply unpublished.
- The indication was derived automatically from the Condition field of 2 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 0 · preclinical 0
No human studies were found within the sources searched. This means "not yet studied", not "does not work".
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Gardenia jasminoides") OR (TITLE_ABS:"Gardenia augusta") OR (TITLE_ABS:"Gardenia florida")) AND TITLE_ABS:"Overweight and Obesity"Clinical trials
- NCT06333496 — COMPLETED · NA
- NCT07141472 — COMPLETED · NA
Safety
auto-proposed · unreviewed
- 29 adverse-event or toxicity record(s) were found. This only flags that literature exists — read the abstracts to decide between "caution" and "harm confirmed".
Adverse-event and toxicity literature
This is not a finding of harm — it lists literature that is retrievable. Read the papers to decide.
- Hepatic and Renal Toxicity of Gardenia Yellow: Repeated-Dose Assessment and Human Oral Equivalent Dose Prediction via IVIVE. (2025 · Journal Article)
- Genipin rewires endogenous amino acid metabolism and induces hepatocellular necroptosis by activation of the TNF-necrosome signaling axis. (2026 · Research Support, Non-U.S. Gov't; Journal Article)
- Geniposide induces hepatotoxicity via the bile acid-induced activation of NLRP3 inflammasome and regulation of the FXR/PERK/TXNIP pathway. (2025 · Journal Article)
- Geniposidic Acid Targeting FXR "S332 and H447" Mediated Conformational Change to Upregulate CYPs and miR-19a-3p to Ameliorate Drug-Induced Liver Injury. (2025 · research-article; Journal Article)
- Construction of an explanatory model for predicting hepatotoxicity: a case study of the potentially hepatotoxic components of Gardenia jasminoides. (2025 · Journal Article)
Sources
Bridges from here
- In formulas
- 용담사간탕
- Related patterns
- Liver meridian dampness-heat pattern