Mulberry leaf 桑葉
Pharmaceutical nameMori Folium
The three axes are assessed independently and are never combined into a single score.
KTKP records the origin species as Morus alba L.. It has not yet been cross-checked against the Korean Pharmacopoeia, so the identification confidence is not raised to an official code mapping. The same drug appears under 6 records as name variants. The same source species also yields 6 other separately registered drug(s) (Mori Fructus, Mori Favilla, Mori Radicis Cortex, Morus Cortex, Mori Ramulus, Mori Cortex), which must not be conflated. The name most used for this taxon in current literature is Morus alba. Literature searches for this herb also cover Morus multicaulis, Morus alba var. multicaulis — the same taxon appears under several names.
Tradition · what the text describes
탕액편
The sub-section within this volume has not been verified against the original text yet.
The KTKP traditional materia medica record (M0000151) gives the origin species as Morus alba L., the part used as 잎, and the properties as 고감(苦甘), 한(寒). It lists 간(肝), 폐(肺) as the channels entered.
Properties & channel entry: 고감(苦甘), 한(寒) · 간(肝), 폐(肺)
Source species: Morus alba L. (잎)
Modern · documented evidence
Diabetes Mellitus, Type 2evidence for this indication
- 5 registered trial(s) exist but no published systematic review or RCT was found. Check whether the research is ongoing or simply unpublished.
- The indication was derived automatically from the Condition field of 0 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 0 · preclinical 0
No human studies were found within the sources searched. This means "not yet studied", not "does not work".
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Morus alba") OR (TITLE_ABS:"Morus multicaulis") OR (TITLE_ABS:"Morus alba var. multicaulis")) AND TITLE_ABS:"Diabetes Mellitus, Type 2"Clinical trials
- NCT03807570 — UNKNOWN · NA
- NCT07532135 — RECRUITING · PHASE1
- NCT03475394 — COMPLETED · NA
- NCT06509204 — COMPLETED · NA
- NCT06911073 — COMPLETED · NA
Safety
auto-proposed · unreviewed
- This signal was read off the NCCIH text by keyword rules. A curator must read the source and confirm it.
- NCCIH states: · The most common side effect is digestive upset, including bloating, constipation, gas, and loose stools.
- NCCIH states: · Little is known about whether it’s safe to use white mulberry leaf during pregnancy or while breastfeeding.
Adverse-event and toxicity literature
This is not a finding of harm — it lists literature that is retrievable. Read the papers to decide.
- Bioactivity, phytochemistry studies and subacute in vivo toxicity of ethanolic leaf extract of white mulberry (Morus alba linn.) in female mice. (2024 · Journal Article)
- Subchronic oral toxicity study of the synbiotic mulberry in male and female Wistar rats. (2024 · Journal Article)
- A 90-day preclinical toxicological evaluation in rats of a highly purified and concentrated mulberry leaf extract. (2024 · Research Support, Non-U.S. Gov't; Journal Article)
- Identification of Renoprotective Phytosterols from Mulberry (Morus alba) Fruit against Cisplatin-Induced Cytotoxicity in LLC-PK1 Kidney Cells. (2021 · research-article; Journal Article)
- Pharmacological and Clinical Studies of Medicinal Plants That Inhibit Dipeptidyl Peptidase-IV. (2023 · review-article; Review; Journal Article)
Interaction literature
This lists literature that is retrievable — it is not a judgement that an interaction exists. Read the papers to decide.
- Mulberrofuran G, a Mulberry Component, Prevents SARS-CoV-2 Infection by Blocking the Interaction between SARS-CoV-2 Spike Protein S1 Receptor-Binding Domain and Human Angiotensin-Converting Enzyme 2 Receptor. (2022 · research-article; Journal Article)
- [Advances in the pharmacological study of Morus alba L]. (2014 · Review; Journal Article)
- Herb-drug interaction between an anti-HIV Chinese herbal SH formula and atazanavir in vitro and in vivo. (2015 · Research Support, Non-U.S. Gov't; Journal Article)
- [Evaluate drug interaction of multi-components in Morus alba leaves based on α-glucosidase inhibitory activity]. (2016 · Journal Article)
- Down-regulation of P-gp expression and function after Mulberroside A treatment: potential role of protein kinase C and NF-kappa B. (2014 · Research Support, Non-U.S. Gov't; Journal Article)
Sources
Bridges from here
- In formulas
- 단삼음자