Perilla leaf 紫蘇葉
Pharmaceutical namePerillae Folium
The three axes are assessed independently and are never combined into a single score.
KTKP records the origin species as Perilla frutescens (L.) Brit.. It has not yet been cross-checked against the Korean Pharmacopoeia, so the identification confidence is not raised to an official code mapping. The same drug appears under 2 records as name variants. The same source species also yields 7 other separately registered drug(s) (Perilliae Semen, Perillae Caulis, Perilla Herba, Perilla Folium, Perillae Frutescens Semen, Perillae Herba, Perillae Frutescens Folium), which must not be conflated. The name most used for this taxon in current literature is Perilla frutescens. Literature searches for this herb also cover Perilla frutescens var. crispa, Perilla frutescens var. acuta, Perilla ocymoides — the same taxon appears under several names. The nomenclatural discussion for this herb was flagged for correction during verification; only the verified facts are shown here, with the details in docs/HERB_NAME_RESEARCH.md.
Tradition · what the text describes
탕액편
The sub-section within this volume has not been verified against the original text yet.
The KTKP traditional materia medica record (M0003098) gives the origin species as Perilla frutescens (L.) Brit., the part used as 잎, and the properties as 신(辛), 온(溫). It lists 비(脾), 심(心) as the channels entered. The same record cites the Donguibogam (1613) as the source for its indications.
Properties & channel entry: 신(辛), 온(溫) · 비(脾), 심(心)
Source species: Perilla frutescens (L.) Brit. (잎)
Modern · documented evidence
Allergic Rhinitisevidence for this indication
- The indication was derived automatically from the Condition field of 2 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 2 · RCT 1 · preclinical 3
2 systematic review(s) and 1 RCT(s) were found. Size and consistency are not yet assessed.
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Perilla frutescens") OR (TITLE_ABS:"Perilla frutescens var. crispa") OR (TITLE_ABS:"Perilla frutescens var. acuta") OR (TITLE_ABS:"Perilla ocymoides")) AND TITLE_ABS:"Allergic Rhinitis"- Synergic Efficacy of a Multicomponent Nutraceutical Add-On Therapy in Seasonal Allergic Rhinitis in Children: A Prospective, Randomized, Parallel-Group Study. (2025 · research-article; Journal Article)
- Exploratory pilot trial of a multicomponent immunonutritional supplement in children with allergic asthma and rhinitis: The INAPRA study. (2026 · Multicenter Study; Randomized Controlled Trial; Journal Article)
- Effect of Traditional Chinese Medicine on Allergic Rhinitis in Children under Data Mining. (2022 · Retracted Publication; research-article; Journal Article)
- Health supplements for allergic rhinitis: A mixed-methods systematic review. (2020 · Systematic Review; Journal Article)
- Luteolin Attenuates Allergic Nasal Inflammation via Inhibition of Interleukin-4 in an Allergic Rhinitis Mouse Model and Peripheral Blood From Human Subjects With Allergic Rhinitis. (2020 · research-article; Journal Article)
- Effect of Perilla frutescens var. acuta Kudo and rosmarinic acid on allergic inflammatory reactions. (2011 · Research Support, Non-U.S. Gov't; Journal Article)
- A flavanone derivative from the Asian medicinal herb (Perilla frutescens) potently suppresses IgE-mediated immediate hypersensitivity reactions. (2017 · Research Support, Non-U.S. Gov't; Journal Article)
- Efficacy of a novel food supplement in the relief of the signs and symptoms of seasonal allergic rhinitis and in the reduction of the consumption of anti-allergic drugs. (2015 · Clinical Study; Journal Article)
Clinical trials
- NCT07016763 — COMPLETED · EARLY_PHASE1
- NCT07308288 — COMPLETED · NA
Safety
auto-proposed · unreviewed
- 13 adverse-event or toxicity record(s) were found. This only flags that literature exists — read the abstracts to decide between "caution" and "harm confirmed".
- 1 interaction-related record(s) are retrievable. This flags that literature exists — it is not an interaction checker (§3.4).
- The KTKP record states the following traditional contraindication: 복용 중 잉어를 먹지 말 것. 온병(溫病), 허약과로자(虛弱過勞者)는 먹지 말 것.
Adverse-event and toxicity literature
This is not a finding of harm — it lists literature that is retrievable. Read the papers to decide.
- Axillary Hyperpigmentation Treatment: A Systematic Review of the Literature. (2025 · Systematic Review; review-article; Journal Article)
- Immunonutritional effects elicited by a novel multicomponent food supplement in children with cow's milk allergy: results from a randomized, placebo-controlled trial. (2026 · Clinical Trial; research-article; Journal Article)
- Exploratory pilot trial of a multicomponent immunonutritional supplement in children with allergic asthma and rhinitis: The INAPRA study. (2026 · Multicenter Study; Randomized Controlled Trial; Journal Article)
- Efficacy of Perilla frutescens (L.) Britton var. frutescens extract on mild knee joint pain: A randomized controlled trial. (2023 · research-article; Journal Article)
- Leaf-associated microbiota on perilla (Perilla frutescens var. frutescens) cultivated in South Korea to detect the potential risk of food poisoning. (2019 · Research Support, Non-U.S. Gov't; Journal Article)
Interaction literature
This lists literature that is retrievable — it is not a judgement that an interaction exists. Read the papers to decide.
- Heterotropic Activation of Cytochrome P450 3A4 by Perillyl Alcohol. (2024 · research-article; Journal Article)
Sources
Bridges from here
- In formulas
- 일복산