Kudzu root 葛根
Pharmaceutical namePuerariae Radix
The three axes are assessed independently and are never combined into a single score.
KTKP records the origin species as Pueraria lobata Benth (Willd.) Ohwi (= Pueraria thunbergiana). It has not yet been cross-checked against the Korean Pharmacopoeia, so the identification confidence is not raised to an official code mapping. The name most used for this taxon in current literature is Pueraria lobata. Literature searches for this herb also cover Pueraria montana var. lobata, Pueraria thunbergiana — the same taxon appears under several names.
Tradition · what the text describes
탕액편
The sub-section within this volume has not been verified against the original text yet.
The KTKP traditional materia medica record (M0000031) gives the origin species as Pueraria lobata Benth (Willd.) Ohwi (= Pueraria thunbergiana), the part used as 뿌리, and the properties as 감신(甘辛), 양(凉). It lists 비(脾), 위(胃) as the channels entered. The same record cites the Donguibogam (1613) as the source for its indications.
Properties & channel entry: 감신(甘辛), 양(凉) · 비(脾), 위(胃)
Source species: Pueraria lobata Benth (Willd.) Ohwi (= Pueraria thunbergiana) (뿌리)
Modern · documented evidence
Alcohol Use Disorderevidence for this indication
- 2 registered trial(s) exist but no published systematic review or RCT was found. Check whether the research is ongoing or simply unpublished.
- The indication was derived automatically from the Condition field of 2 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 0 · preclinical 0
No human studies were found within the sources searched. This means "not yet studied", not "does not work".
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Pueraria lobata") OR (TITLE_ABS:"Pueraria montana var. lobata") OR (TITLE_ABS:"Pueraria thunbergiana")) AND TITLE_ABS:"Alcohol Use Disorder"Clinical trials
- NCT03709043 — COMPLETED · PHASE2
- NCT03099590 — COMPLETED · PHASE2
Menopauseevidence for this indication
- The indication was derived automatically from the Condition field of 2 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 1 · preclinical 6
0 systematic review(s) and 1 RCT(s) were found. Size and consistency are not yet assessed.
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Pueraria lobata") OR (TITLE_ABS:"Pueraria montana var. lobata") OR (TITLE_ABS:"Pueraria thunbergiana")) AND TITLE_ABS:"Menopause"- Effects of Cnidium officinale, Pueraria lobata Ohwi, and Leonurus japonicus Extract on Vascular Endothelial Dysfunctions in Ovariectomized Rats and Molecular Mechanisms. (2025 · research-article; Journal Article)
- Anti-dyslipidemic effects of Pueraria lobata root and Glycine max (L.) Merrill extracts fermented with Lactiplantibacillus plantarum in ovariectomized mice. (2024 · research-article; Journal Article)
- Dietary Puerarin Translocates to Femur and Suppresses Osteoclast Differentiation in Ovariectomized Mice. (2024 · Journal Article)
- Combined Extract of Leonurus japonicus Houtt, Eclipta prostrata L., and Pueraria lobata Ohwi Improved Hot Flashes and Depression in an Ovariectomized Rat Model of Menopause. (2021 · research-article; Journal Article)
- The Efficacy and Safety of Multiple Dose Regimens of Kudzu (Pueraria lobata) Root Extract on Bone and Cartilage Turnover and Menopausal Symptoms. (2021 · research-article; Journal Article)
- Investigating the Systems-Level Effect of Pueraria lobata for Menopause-Related Metabolic Diseases Using an Ovariectomized Rat Model and Network Pharmacological Analysis. (2019 · Research Support, Non-U.S. Gov't; research-article; Journal Article)
- Combination of Sargassum fusiforme and Pueraria lobata Extracts Alleviates Postmenopausal Symptoms in Ovariectomized Rats. (2020 · Journal Article)
- A Herbal Formula HT051, a Combination of Pueraria lobata and Rehmannia glutinosa, Prevents Postmenopausal Obesity in Ovariectomized Rats. (2017 · research-article; Journal Article)
Clinical trials
- NCT04552106 — COMPLETED · NA
- NCT07757724 — COMPLETED · NA
Sleep Initiation and Maintenance Disordersevidence for this indication
- 2 registered trial(s) exist but no published systematic review or RCT was found. Check whether the research is ongoing or simply unpublished.
- The indication was derived automatically from the Condition field of 2 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 0 · preclinical 0
No human studies were found within the sources searched. This means "not yet studied", not "does not work".
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Pueraria lobata") OR (TITLE_ABS:"Pueraria montana var. lobata") OR (TITLE_ABS:"Pueraria thunbergiana")) AND TITLE_ABS:"Sleep Initiation and Maintenance Disorders"Clinical trials
- NCT07788547 — COMPLETED · NA
- NCT07757724 — COMPLETED · NA
Safety
auto-proposed · unreviewed
- 32 adverse-event or toxicity record(s) were found. This only flags that literature exists — read the abstracts to decide between "caution" and "harm confirmed".
- 3 interaction-related record(s) are retrievable. This flags that literature exists — it is not an interaction checker (§3.4).
- The KTKP record states the following traditional contraindication: 위한구토자(胃寒嘔吐者)와 표허한다자(表虛汗多者)는 복용을 기(忌)한다.
Adverse-event and toxicity literature
This is not a finding of harm — it lists literature that is retrievable. Read the papers to decide.
- Roles and mechanisms of Pueraria lobata radix in metabolic dysfunction-associated steatotic liver disease. (2026 · Review; Journal Article)
- Comparison of Alcohol-Induced Hepatoprotective Effects of the High Fischer Ratio Oligopeptides with/Without Half Substitution by Pueraria lobata. (2025 · research-article; Journal Article)
- Network pharmacology combines cellular experiments to investigate the anti-inflammatory phytochemicals of vine of Pueraria montana var. lobata and their mechanism. (2025 · Journal Article)
- Efficacy and safety of Pueraria lobata radix as an adjuvant therapy for type 2 diabetes mellitus: rationale, design and protocol for a randomised controlled trial. (2025 · Clinical Trial Protocol; research-article; Journal Article)
- Preparation of Pueraria lobata Root-Derived Exosome-Like Nanovesicles and Evaluation of Their Effects on Mitigating Alcoholic Intoxication and Promoting Alcohol Metabolism in Mice. (2024 · research-article; Journal Article)
Interaction literature
This lists literature that is retrievable — it is not a judgement that an interaction exists. Read the papers to decide.
- Radix Puerariae: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. (2013 · Research Support, Non-U.S. Gov't; Review; Journal Article)
- In vitro and in vivo evaluation of the effect of puerarin on hepatic cytochrome p450-mediated drug metabolism. (2014 · Research Support, Non-U.S. Gov't; Journal Article)
- The effects of puerarin on CYP2D6 and CYP1A2 activities in vivo. (2010 · Research Support, Non-U.S. Gov't; Journal Article)
Sources
- KTKP materia medica (15002148) (fetched 2026-08-27)
- Europe PMC REST (fetched 2026-08-28)
- ClinicalTrials.gov API v2 (fetched 2026-08-28)
- Europe PMC REST (fetched 2026-08-28)
- ClinicalTrials.gov API v2 (fetched 2026-08-28)
- Europe PMC REST (fetched 2026-08-28)
- ClinicalTrials.gov API v2 (fetched 2026-08-28)
- KTKP materia medica (15002148) (fetched 2026-08-27)
- Europe PMC REST (fetched 2026-08-28)