Rehmannia 地黃
Pharmaceutical nameRehmanniae Radix
The three axes are assessed independently and are never combined into a single score.
KTKP records the origin species as Rehmannia glutinosa (Gaertner) Libosch.. It has not yet been cross-checked against the Korean Pharmacopoeia, so the identification confidence is not raised to an official code mapping. The same drug appears under 10 records as name variants. The same source species also yields 4 other separately registered drug(s) (Rehmanniae Radix Preparat, Rehmanniae Radix Crudus, Rehmanniae Radix Siccus, Rehmanniae Radix et Rhizoma Preparata), which must not be conflated. The name most used for this taxon in current literature is Rehmannia glutinosa.
Tradition · what the text describes
탕액편
The sub-section within this volume has not been verified against the original text yet.
The KTKP traditional materia medica record (M0000118) gives the origin species as Rehmannia glutinosa (Gaertner) Libosch., the part used as 뿌리, and the properties as 감고(甘苦), 양(凉). It lists 간(肝), 신(腎), 심(心) as the channels entered. The same record cites the Donguibogam (1613) as the source for its indications.
Properties & channel entry: 감고(甘苦), 양(凉) · 간(肝), 신(腎), 심(心)
Source species: Rehmannia glutinosa (Gaertner) Libosch. (뿌리)
Modern · documented evidence
Chronic Glomerulonephritisevidence for this indication
- The indication was derived automatically from the Condition field of 0 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 1 · preclinical 3
0 systematic review(s) and 1 RCT(s) were found. Size and consistency are not yet assessed.
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Rehmannia glutinosa")) AND TITLE_ABS:"Chronic Glomerulonephritis"- Study on the mechanism of acteoside in treating purinomycin aminonucleoside-induced chronic glomerulonephritis in childhood rats based on Cxcr4-PI3K-Akt-eNOS axis. (2025 · Journal Article)
- Studies on the metabolism and mechanism of acteoside in treating chronic glomerulonephritis. (2023 · Journal Article)
- Protective Effects of Total Glycoside From Rehmannia glutinosa Leaves on Diabetic Nephropathy Rats via Regulating the Metabolic Profiling and Modulating the TGF-β1 and Wnt/β-Catenin Signaling Pathway. (2018 · research-article; Journal Article)
- Treatment of primary chronic glomerulonephritis with Rehmannia glutinosa acteosides in combination with the angiotensin receptor blocker irbesartan: a randomized controlled trial. (2014 · Randomized Controlled Trial; Journal Article)
Clinical trials
- NCT07145060 — NOT_YET_RECRUITING · NA
- NCT03562429 — UNKNOWN · PHASE2, PHASE3
- NCT04937374 — COMPLETED · NA
- NCT06674252 — RECRUITING · NA
- NCT06583369 — UNKNOWN · NA
Safety
auto-proposed · unreviewed
- 15 adverse-event or toxicity record(s) were found. This only flags that literature exists — read the abstracts to decide between "caution" and "harm confirmed".
- 3 interaction-related record(s) are retrievable. This flags that literature exists — it is not an interaction checker (§3.4).
- The KTKP record states the following traditional contraindication: 무, 마늘, 파 등을 먹으면 안 됨. 쇠붙이에 닿지 않게 함.
Adverse-event and toxicity literature
This is not a finding of harm — it lists literature that is retrievable. Read the papers to decide.
- Rehmannia glutinosa for perimenopausal syndrome in patients with breast cancer: A systematic review and meta-analysis. (2025 · Meta-Analysis; Systematic Review; systematic-review; Journal Article)
- Treatment of acute intracerebral haemorrhage with a Chinese herbal formula (Shengdi Dahuang Decoction): a multicentre, double-blind, randomised, placebo-controlled trial. (2026 · Research Support, Non-U.S. Gov't; research-article; Multicenter Study; Randomized Controlled Trial; Journal Article)
- The coexistence characteristics of microplastics and heavy metals in rhizomes of traditional Chinese medicine in mulch planting area. (2025 · Journal Article)
- Co-catalpol alleviates fluoxetine-induced main toxicity: Involvement of ATF3/FSP1 signaling-mediated inhibition of ferroptosis. (2024 · Journal Article)
- Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties. (2021 · research-article; Journal Article)
Interaction literature
This lists literature that is retrievable — it is not a judgement that an interaction exists. Read the papers to decide.
- Formulation principles and mechanisms of TCM patent prescriptions for PCOS: A data mining study from CNIPA. (2025 · research-article; Journal Article)
- The Evaluation of CP-001 (a Standardized Herbal Mixture of Houttuynia cordata, Rehmannia glutinosa, Betula platyphylla, and Rubus coreanus) for Cytochrome P450-Related Herb-Drug Interactions. (2013 · research-article; Journal Article)
- Effect of Chinese herbs on CYP3A4 activity and expression in vitro. (2013 · Research Support, Non-U.S. Gov't; Journal Article)