Magnolia bark 厚朴
Pharmaceutical nameMagnoliae Cortex
The three axes are assessed independently and are never combined into a single score.
KTKP records the origin species as Magnolia officinalis Rehder et Wilson. It has not yet been cross-checked against the Korean Pharmacopoeia, so the identification confidence is not raised to an official code mapping. The same drug appears under 2 records as name variants. The name most used for this taxon in current literature is Magnolia officinalis. Literature searches for this herb also cover Magnolia officinalis var. biloba, Houpoea officinalis — the same taxon appears under several names.
Tradition · what the text describes
탕액편
The sub-section within this volume has not been verified against the original text yet.
The KTKP traditional materia medica record (M0004444) gives the origin species as Magnolia officinalis Rehder et Wilson, the part used as 껍질, and the properties as 고신(苦辛), 무독(無毒), 온(溫). It lists 대장(大腸), 비(脾), 위(胃), 폐(肺) as the channels entered. The same record cites the Donguibogam (1613) as the source for its indications.
Properties & channel entry: 고신(苦辛), 무독(無毒), 온(溫) · 대장(大腸), 비(脾), 위(胃), 폐(肺)
Source species: Magnolia officinalis Rehder et Wilson (껍질)
Modern · documented evidence
Non-alcoholic Fatty Liver Diseaseevidence for this indication
- 5 registered trial(s) exist but no published systematic review or RCT was found. Check whether the research is ongoing or simply unpublished.
- The indication was derived automatically from the Condition field of 0 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 0 · preclinical 1
No human clinical literature found; 1 preclinical (in vitro/animal) record(s) only.
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Magnolia officinalis") OR (TITLE_ABS:"Magnolia officinalis var. biloba") OR (TITLE_ABS:"Houpoea officinalis")) AND TITLE_ABS:"Non-alcoholic Fatty Liver Disease"- The natural compounds, Magnolol or Honokiol, promote adipose tissue browning and resist obesity through modulating PPARα/γ activity. (2024 · Journal Article)
Clinical trials
- NCT07471048 — RECRUITING · NA
- NCT03364101 — COMPLETED · NA
- NCT07721012 — NOT_YET_RECRUITING · PHASE2
- NCT07712081 — COMPLETED · NA
- NCT04517045 — UNKNOWN · PHASE2, PHASE3
Safety
auto-proposed · unreviewed
- 10 adverse-event or toxicity record(s) were found. This only flags that literature exists — read the abstracts to decide between "caution" and "harm confirmed".
- The KTKP record states the following traditional contraindication: 고신온(苦辛溫)하므로 음허내열(陰虛內熱)하여 진액(津液)이 고갈(枯渴)된 자는 복용을 기(忌)한다.
Adverse-event and toxicity literature
This is not a finding of harm — it lists literature that is retrievable. Read the papers to decide.
- Development and Characterization of Intravenous Nanoemulsions Loaded with Magnolia officinalis Neolignans. (2026 · research-article; Journal Article)
- Magnolia Officinalis Alcohol Extract Alleviates the Intestinal Injury Induced by Polygala Tenuifolia Through Regulating the PI3K/AKT/NF-κB Signaling Pathway and Intestinal Flora. (2024 · research-article; Journal Article)
- Honokiol alleviates acetaminophen-induced hepatotoxicity via decreasing generation of acetaminophen-protein adducts in liver. (2019 · Journal Article)
- Honokiol, a Polyphenol Natural Compound, Attenuates Cisplatin-Induced Acute Cytotoxicity in Renal Epithelial Cells Through Cellular Oxidative Stress and Cytoskeleton Modulations. (2018 · research-article; Journal Article)
- Safety and Toxicology of Magnolol and Honokiol. (2018 · Review; Journal Article)
Sources
Bridges from here
- In formulas
- 실장산 · 지축이진탕 · 오격관중산 · 침향강기산 · 생료오적산 · 곽향정기산 · 반하후박탕 · 십육미류기음
- Related patterns
- Block and repulsion disorder · Wind-cold pattern · Qi stagnation pattern · Qi uprising pattern · Large intestine deficiency cold pattern