Peony root 芍藥
Pharmaceutical namePaeoniae Radix
The three axes are assessed independently and are never combined into a single score.
KTKP records the origin species as Paeonia lactiflora Pallas. It has not yet been cross-checked against the Korean Pharmacopoeia, so the identification confidence is not raised to an official code mapping. The same drug appears under 2 records as name variants. The same source species also yields 3 other separately registered drug(s) (Paeoniae Radix Alba, Paeoniae Radix Rubra, Peaoniae Radix), which must not be conflated. The name most used for this taxon in current literature is Paeonia lactiflora. Literature searches for this herb also cover Paeoniae lactiflora — the same taxon appears under several names. The nomenclatural discussion for this herb was flagged for correction during verification; only the verified facts are shown here, with the details in docs/HERB_NAME_RESEARCH.md.
Tradition · what the text describes
탕액편
The sub-section within this volume has not been verified against the original text yet.
The KTKP traditional materia medica record (M0003179) gives the origin species as Paeonia lactiflora Pallas, the part used as 뿌리, and the properties as 고산(苦酸), 미한(微寒). It lists 간(肝), 비(脾), 폐(肺) as the channels entered. The same record cites the Donguibogam (1613) as the source for its indications.
Properties & channel entry: 고산(苦酸), 미한(微寒) · 간(肝), 비(脾), 폐(肺)
Source species: Paeonia lactiflora Pallas (뿌리)
Modern · documented evidence
Irritable Bowel Syndromeevidence for this indication
- Systematic reviews were found but no RCTs. Check the search query (queryUsed).
- The indication was derived automatically from the Condition field of 4 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 1 · RCT 0 · preclinical 2
1 systematic review(s) and 0 RCT(s) were found. Size and consistency are not yet assessed.
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Paeonia lactiflora") OR (TITLE_ABS:"Paeoniae lactiflora")) AND TITLE_ABS:"Irritable Bowel Syndrome"- Atractylodes macrocephala-Paeonia lactiflora Class Formula for the Treatment of Irritable Bowel Syndrome: A Systematic Review With Meta-Analysis and Trial Sequential Analysis. (2023 · review-article; Review; Journal Article)
- Systematic review and meta-analysis of Chinese herbal formula Tongxie Yaofang for diarrhea-predominant irritable bowel syndrome: Evidence for clinical practice and future trials. (2022 · Systematic Review; systematic-review; Journal Article)
- Chinese herbal formula Tongxie Yaofang for diarrhea-predominant irritable bowel syndrome: study protocol for a randomized, multiple-blind, placebo-controlled trial. (2022 · Clinical Trial Protocol; research-article; Journal Article)
- Effects of Trang Phuc Linh Plus-Food Supplement on Irritable Bowel Syndrome Induced by Mustard Oil. (2017 · Journal Article)
- The analgesic effect of paeoniflorin on neonatal maternal separation-induced visceral hyperalgesia in rats. (2008 · Research Support, Non-U.S. Gov't; Journal Article)
Clinical trials
- NCT01641224 — UNKNOWN · NA
- NCT02330029 — UNKNOWN · NA
- NCT02653937 — COMPLETED · NA
- NCT00676975 — COMPLETED · PHASE2
Infertility, Femaleevidence for this indication
- 2 registered trial(s) exist but no published systematic review or RCT was found. Check whether the research is ongoing or simply unpublished.
- The indication was derived automatically from the Condition field of 2 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 0 · preclinical 0
No human studies were found within the sources searched. This means "not yet studied", not "does not work".
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Paeonia lactiflora") OR (TITLE_ABS:"Paeoniae lactiflora")) AND TITLE_ABS:"Infertility, Female"Clinical trials
- NCT05698550 — COMPLETED · NA
- NCT05577455 — UNKNOWN · PHASE3
Safety
auto-proposed · unreviewed
- 21 adverse-event or toxicity record(s) were found. This only flags that literature exists — read the abstracts to decide between "caution" and "harm confirmed".
- 1 interaction-related record(s) are retrievable. This flags that literature exists — it is not an interaction checker (§3.4).
- The KTKP record states the following traditional contraindication: 여로(藜蘆)와 같이 쓰지 말 것. 허한(虛寒)에 의한 복통(腹痛), 설사자(泄瀉者)는 복용에 주의함.
Adverse-event and toxicity literature
This is not a finding of harm — it lists literature that is retrievable. Read the papers to decide.
- Dual mechanisms of a purified root extract of Paeonia lactiflora Pall. in regulating uric acid homeostasis: inhibition of hepatic synthesis and promotion of renal excretion in hyperuricemic rat models. (2026 · research-article; Journal Article)
- Integrating high-resolution bioassay profiling with affinity-based ligand fishing for unveiling galloylated derivatives as novel catechol-O-methyltransferase inhibitors in Paeonia lactiflora Pall. (2026 · research-article; Journal Article)
- Cardiovascular Evaluations of a Mixed Extract of Salvia Miltiorrhiza Bunge and Paeonia Lactiflora Pall. (USCP-GVH-014): A 12 Weeks Clinical Perspective. (2025 · Clinical Trial; Journal Article)
- Traditional Chinese Medicine Interventions for Antipsychotic-Induced Extrapyramidal Symptoms: A Data Mining-Based Integrative Review of Prescription Patterns and Evidence. (2026 · Review; Journal Article)
- Atractylodes macrocephala-Paeonia lactiflora Class Formula for the Treatment of Irritable Bowel Syndrome: A Systematic Review With Meta-Analysis and Trial Sequential Analysis. (2023 · review-article; Review; Journal Article)
Interaction literature
This lists literature that is retrievable — it is not a judgement that an interaction exists. Read the papers to decide.
- Chinese herbal formulae for the treatment of menopausal hot flushes: A systematic review and meta-analysis. (2019 · Meta-Analysis; research-article; Systematic Review; Journal Article)
Sources
- KTKP materia medica (15002148) (fetched 2026-08-27)
- Europe PMC REST (fetched 2026-08-28)
- ClinicalTrials.gov API v2 (fetched 2026-08-28)
- Europe PMC REST (fetched 2026-08-28)
- ClinicalTrials.gov API v2 (fetched 2026-08-28)
- KTKP materia medica (15002148) (fetched 2026-08-27)
- Europe PMC REST (fetched 2026-08-28)
Bridges from here
- In formulas
- 계마각반탕 · 시호계지탕 · 십육미류기음
- Related patterns
- Neck stiffness disorder · Early yang stage pattern · Yang collapse pattern