Korean angelica 當歸
Pharmaceutical nameAngelicae Gigantis Radix
The three axes are assessed independently and are never combined into a single score.
KTKP records the origin species as Angelica gigas Nakai. It has not yet been cross-checked against the Korean Pharmacopoeia, so the identification confidence is not raised to an official code mapping. The same drug appears under 2 records as name variants. The name most used for this taxon in current literature is Angelica gigas. Literature searches for this herb also cover Angelicae gigas — the same taxon appears under several names.
Tradition · what the text describes
탕액편
The sub-section within this volume has not been verified against the original text yet.
The KTKP traditional materia medica record (M0000820) gives the origin species as Angelica gigas Nakai, the part used as 뿌리, and the properties as 감신(甘辛), 무독(無毒), 온(溫). It lists 간(肝), 비(脾), 심(心) as the channels entered. The same record cites the Donguibogam (1613) as the source for its indications.
Properties & channel entry: 감신(甘辛), 무독(無毒), 온(溫) · 간(肝), 비(脾), 심(心)
Source species: Angelica gigas Nakai (뿌리)
Modern · documented evidence
Prostate Cancerevidence for this indication
- 2 registered trial(s) exist but no published systematic review or RCT was found. Check whether the research is ongoing or simply unpublished.
- The indication was derived automatically from the Condition field of 2 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 0 · preclinical 6
No human clinical literature found; 6 preclinical (in vitro/animal) record(s) only.
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Angelica gigas") OR (TITLE_ABS:"Angelicae gigas")) AND TITLE_ABS:"Prostate Cancer"- Angelica gigas Nakai (Korean Dang-gui) Root Alcoholic Extracts in Health Promotion and Disease Therapy - active Phytochemicals and In Vivo Molecular Targets. (2025 · research-article; Journal Article)
- Effects of decursinol angelate on viability and apoptosis in PC-3 prostate cancer cells: In vitro study. (2024 · research-article; Journal Article)
- Antitumor mechanism of combination of Angelica gigas and Torilis japonica in LNCaP prostate cancer cells via G1 arrest and inhibition of Wnt/β-catenin and androgen receptor signaling. (2022 · Journal Article)
- Interception Targets of Angelica Gigas Nakai Root Extract versus Pyranocoumarins in Prostate Early Lesions and Neuroendocrine Carcinomas in TRAMP Mice. (2021 · Comparative Study; Research Support, Non-U.S. Gov't; research-article; Journal Article; Research Support, N.I.H., Extramural)
- Prostate Cancer Xenograft Inhibitory Activity and Pharmacokinetics of Decursinol, a Metabolite of Angelica gigas Pyranocoumarins, in Mouse Models. (2017 · research-article; Journal Article)
- A potential treatment option for elderly non-Hodgkin lymphoma patients with multiple comorbidities: Two case reports and literature review. (2021 · Review; Journal Article; Case Reports)
- SH003 induces apoptosis of DU145 prostate cancer cells by inhibiting ERK-involved pathway. (2016 · research-article; Journal Article)
- Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds. (2012 · Research Support, Non-U.S. Gov't; Review; Journal Article; Research Support, N.I.H., Extramural)
Clinical trials
- NCT06600698 — RECRUITING · PHASE1, PHASE2
- NCT05375539 — COMPLETED · PHASE1
Safety
auto-proposed · unreviewed
- 11 adverse-event or toxicity record(s) were found. This only flags that literature exists — read the abstracts to decide between "caution" and "harm confirmed".
- 1 interaction-related record(s) are retrievable. This flags that literature exists — it is not an interaction checker (§3.4).
- The KTKP record states the following traditional contraindication: 윤활(潤滑)한 성질이 있으므로 습조중만(濕阻中滿)의 경우 또는 대변당설(大便溏泄)의 경우에는 신용(愼用)한다. 또한 행혈(行血)하는 작용이 있어 붕루(崩漏)나 나월경과다(羅月經過多), 어체(瘀滯)가 없는 자(者) 등에 신용(愼用)한다. 당귀(當歸)를 장기간 혹은 다량 복용하면 인후통(咽喉痛), 비공(鼻孔)의 작열감 등의 허화상염(虛火上炎)의 증상이 나타날 수도 있다. 또한 출혈성환자에는 초기에 활혈(活血)의 효능이 있어 신용(愼用)한다. 그러나 만성(慢性)에는 교애사물탕(膠艾四物湯)과 같이 보혈(補血)을 겸한 치료법에서 응용된다.
Adverse-event and toxicity literature
This is not a finding of harm — it lists literature that is retrievable. Read the papers to decide.
- SHPro® (mixture of Angelica gigas and Astragalus membranaceus) in men with lower urinary tract symptoms: A randomized, double-blind, placebo-controlled clinical trial. (2025 · Research Support, Non-U.S. Gov't; research-article; Randomized Controlled Trial; Journal Article)
- Combining UHPLC profiling and random walk network-based in vitro analysis to predict herb-induced liver injury. (2026 · Journal Article)
- Hematopoietic Effects of Angelica gigas Nakai Extract on Cyclophosphamide-Induced Myelosuppression. (2022 · research-article; Journal Article)
- Safety Evaluation of SH003 and Docetaxel Combination in Patients With Breast and Lung Cancer: A Multi-Center, Open-Label, Dose Escalation Phase I Clinical Trial. (2025 · Research Support, Non-U.S. Gov't; research-article; Multicenter Study; Clinical Trial, Phase I; Journal Article)
- Herbal therapeutics for female infertility: A systematic review and meta-analysis. (2024 · Meta-Analysis; Systematic Review; Journal Article)
Interaction literature
This lists literature that is retrievable — it is not a judgement that an interaction exists. Read the papers to decide.
- JI017 Sensitizes EGFR-T790M NSCLC to Erlotinib by Extinguishing the STAT3-Survivin Axis. (2026 · Journal Article)
Sources
Bridges from here
- In formulas
- 가구자원 · 계령탕 · 기침산 · 당귀작약탕 · 사물탕 · 사청환 · 영지원 · 용담사간탕 · 자음건비탕 · 혈풍탕 · 호골산 · 경험이방음 · 당귀사역탕 · 신성복기탕 · 양혈거풍탕 · 사순청량음 · 익기안신탕 · 자혈양근탕 · 청신해어탕 · 당귀윤조탕 · 속사단 · 윤폐활담영수탕 · 승준환 · 방풍천마산 · 신기산 · 거풍지보단 · 생료오적산 · 시호방귀탕 · 내탁천금산 · 대온경탕 · 반하후박탕 · 방풍통성산 · 천왕보심단 · 우황청심원 · 형개연교탕 · 십육미류기음
- Related patterns
- Joint-running wind disorder · Crane-knee arthritis disorder · Food retention disorder · Vomiting and diarrhea disorder · Pudendal cold disorder · Puerperal abdominal pain disorder · Puerperal wind disorder · Wind-cold pattern · Wind-heat pattern · Wind-dampness pattern · Cold-dampness pattern · Late yin stage pattern · Blood phase pattern · Blood patterns · Blood deficiency pattern · Blood dryness pattern · Blood heat pattern · Yin deficiency pattern · Yang deficiency pattern · Qi-blood deficiency pattern · Liver deficiency patterns · Liver excess patterns · Liver meridian dampness-heat pattern · Heart deficiency patterns · Heart blood deficiency pattern · Phlegm confounding the orifices of the heart pattern · Middle qi sinking pattern · Lung excess patterns · Kidney yang deficiency pattern · Heart and spleen deficiency pattern