Siler root 防風
Pharmaceutical nameSaposhnikovia Radix
The three axes are assessed independently and are never combined into a single score.
KTKP records the origin species as Saposhnikovia divaricata Schiskin (= Siler divaricatum). It has not yet been cross-checked against the Korean Pharmacopoeia, so the identification confidence is not raised to an official code mapping. The same drug appears under 3 records as name variants. The name most used for this taxon in current literature is Saposhnikovia divaricata. Literature searches for this herb also cover Ledebouriella seseloides, Ledebouriella divaricata — the same taxon appears under several names. The nomenclatural discussion for this herb was flagged for correction during verification; only the verified facts are shown here, with the details in docs/HERB_NAME_RESEARCH.md.
Tradition · what the text describes
탕액편
The sub-section within this volume has not been verified against the original text yet.
The KTKP traditional materia medica record (M0001322) gives the origin species as Saposhnikovia divaricata Schiskin (= Siler divaricatum), the part used as 뿌리, 뿌리줄기, and the properties as 무독(無毒), 신감(辛甘), 온(溫). It lists 간(肝), 방광(膀胱), 비(脾) as the channels entered. The same record cites the Donguibogam (1613) as the source for its indications.
Properties & channel entry: 무독(無毒), 신감(辛甘), 온(溫) · 간(肝), 방광(膀胱), 비(脾)
Source species: Saposhnikovia divaricata Schiskin (= Siler divaricatum) (뿌리, 뿌리줄기)
Modern · documented evidence
Sciaticaevidence for this indication
- 3 registered trial(s) exist but no published systematic review or RCT was found. Check whether the research is ongoing or simply unpublished.
- The indication was derived automatically from the Condition field of 3 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 0 · preclinical 0
No human studies were found within the sources searched. This means "not yet studied", not "does not work".
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Saposhnikovia divaricata") OR (TITLE_ABS:"Ledebouriella seseloides") OR (TITLE_ABS:"Ledebouriella divaricata")) AND TITLE_ABS:"Sciatica"Clinical trials
- NCT03879447 — ACTIVE_NOT_RECRUITING
- NCT03571503 — COMPLETED
- NCT03750591 — COMPLETED
Lumbar Spinal Stenosisevidence for this indication
- 2 registered trial(s) exist but no published systematic review or RCT was found. Check whether the research is ongoing or simply unpublished.
- The indication was derived automatically from the Condition field of 2 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 0 · preclinical 0
No human studies were found within the sources searched. This means "not yet studied", not "does not work".
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Saposhnikovia divaricata") OR (TITLE_ABS:"Ledebouriella seseloides") OR (TITLE_ABS:"Ledebouriella divaricata")) AND TITLE_ABS:"Lumbar Spinal Stenosis"Clinical trials
- NCT03879447 — ACTIVE_NOT_RECRUITING
- NCT02975011 — TERMINATED
Intervertebral Disc Displacementevidence for this indication
- 2 registered trial(s) exist but no published systematic review or RCT was found. Check whether the research is ongoing or simply unpublished.
- The indication was derived automatically from the Condition field of 2 registered trial(s). It reflects what is currently being studied, not a traditional use, and a curator should confirm the label is apt.
Literature
SR 0 · RCT 0 · preclinical 0
No human studies were found within the sources searched. This means "not yet studied", not "does not work".
Query used
We publish the exact query behind these counts so you can reproduce them yourself.
SRC:MED AND ((TITLE_ABS:"Saposhnikovia divaricata") OR (TITLE_ABS:"Ledebouriella seseloides") OR (TITLE_ABS:"Ledebouriella divaricata")) AND TITLE_ABS:"Intervertebral Disc Displacement"Clinical trials
- NCT03571503 — COMPLETED
- NCT03750591 — COMPLETED
Safety
auto-proposed · unreviewed
- 9 adverse-event or toxicity record(s) were found. This only flags that literature exists — read the abstracts to decide between "caution" and "harm confirmed".
- 1 interaction-related record(s) are retrievable. This flags that literature exists — it is not an interaction checker (§3.4).
- The KTKP record states the following traditional contraindication: 음허화왕(陰虛火旺)이나 혈허(血虛)로 인한 경급(痙急)과 두통(頭痛)이 풍사(風邪)로 인하지 않은 경우에는 복용을 균기(均忌)한다. 자한(自汗), 산후발경(産後發痙), 소아발휵(小兒發搐)에는 복용하지 말 것
Adverse-event and toxicity literature
This is not a finding of harm — it lists literature that is retrievable. Read the papers to decide.
- SP-3 Ameliorates Established Cyclophosphamide-Induced Liver Injury and Is Associated with PPAR-Related Transcriptional and Lipid-Metabolic Changes. (2026 · Journal Article)
- Mechanisms of Saposhnikovia divaricata in attenuating NaAsO2-induced neural injury via the PI3K/AKT pathway. (2025 · research-article; Journal Article)
- Efficacy of Yupingfeng powder in the treatment of bronchial asthma in adults: a systematic review and meta-analysis. (2026 · Systematic Review; systematic-review; Journal Article)
- Yupingfeng San extract ameliorates cisplatin induced renal interstitial fibrosis via IL-6/JAK/STAT3 mediated restoration of mitochondrial homeostasis. (2026 · Journal Article)
- Systematic review and meta-analysis of Chinese herbal formula Tongxie Yaofang for diarrhea-predominant irritable bowel syndrome: Evidence for clinical practice and future trials. (2022 · Systematic Review; systematic-review; Journal Article)
Interaction literature
This lists literature that is retrievable — it is not a judgement that an interaction exists. Read the papers to decide.
- Inhibitory potential of herbal medicines on human cytochrome P450-mediated oxidation: properties of umbelliferous or citrus crude drugs and their relative prescriptions. (2001 · Research Support, Non-U.S. Gov't; Journal Article)
Sources
- KTKP materia medica (15002148) (fetched 2026-08-27)
- Europe PMC REST (fetched 2026-08-28)
- ClinicalTrials.gov API v2 (fetched 2026-08-28)
- Europe PMC REST (fetched 2026-08-28)
- ClinicalTrials.gov API v2 (fetched 2026-08-28)
- Europe PMC REST (fetched 2026-08-28)
- ClinicalTrials.gov API v2 (fetched 2026-08-28)
- KTKP materia medica (15002148) (fetched 2026-08-27)
- Europe PMC REST (fetched 2026-08-28)
Bridges from here
- In formulas
- 사청환 · 진액단 · 행습유기산 · 혈풍탕 · 호골산 · 경험이방음 · 신성복기탕 · 양혈거풍탕 · 자혈양근탕 · 청신해어탕 · 승준환 · 방풍천마산 · 거풍지보단 · 시호방귀탕 · 청신익기탕 · 내탁천금산 · 대아교원 · 방풍통성산 · 우황청심원 · 형개연교탕 · 십육미류기음
- Related patterns
- Joint impediment disorders · Joint-running wind disorder · Crane-knee arthritis disorder · Food retention disorder · Vomiting and diarrhea disorder · Pudendal cold disorder · Puerperal wind disorder · Wind-heat pattern · Wind-dampness pattern · Cold-dampness pattern · Dampness-heat pattern · Qi-blood deficiency pattern · Yin-yang deficiency pattern · Liver deficiency patterns · Liver excess patterns · Phlegm confounding the orifices of the heart pattern · Lung excess patterns